Yes ✅ — Metoprolol can cause lichen planus, but it is rare.

More accurately, it can cause a condition called:👉 Lichenoid

Drug Eruption (LDE)

This looks very similar to classical lichen planus but is triggered by a medication.

💊 Beta-blockers & Lichen Planus

Beta blockers including:

• Metoprolol

• Propranolol

• Atenolol

have been reported to cause lichenoid eruptions.

🔬 What Happens?

Metoprolol may trigger a T-cell–mediated immune reaction, leading to skin lesions that resemble lichen planus.

📍 How to Differentiate?

⏳ When Does It Appear?

Usually:

• 1–6 months after starting metoprolol

• Sometimes even later

🔁 Does It Go Away?

Yes 👍
If metoprolol is the cause:

• Lesions improve after stopping the drug

• May take weeks to months to fully clear

• Topical steroids help during recovery

⚠ Never stop metoprolol suddenly — consult doctor first.

🩺 What Should Be Done?

If a patient on metoprolol develops lichen planus-like rash:

1. Clinical evaluation

2. Review drug history

3. Consider biopsy if needed

4. Doctor may switch to another antihypertensive (e.g., ACE inhibitor or CCB)

🎯 Final Answer:

✔ Yes, metoprolol can rarely cause a lichenoid drug eruption, which mimics lichen planus.