Sure! Here’s a that help in clinical decision-making, along with their purpose and what they indicate:
Purpose: Measures creatinine level in blood.
Indicates: Kidney filtration function; high values suggest impaired kidney function.
Purpose: Calculated from serum creatinine, age, sex, race.
Indicates: Overall kidney function; lower eGFR means worse kidney function.
Used for: CKD staging and monitoring progression.
Purpose: Measures urea level in blood.
Indicates: Kidney function and hydration status.
Note: Can be elevated in dehydration or high protein intake, not just kidney disease.
Purpose: Examines urine for protein, blood, glucose, sediments, cells.
Indicates: Signs of infection, inflammation, glomerular disease, or other abnormalities.
Purpose: Detects albuminuria, early kidney damage.
Indicates: Early kidney disease, especially in diabetes or hypertension.
Purpose: Measures creatinine in urine.
Indicates: Used to normalize albumin or protein excretion; also evaluates muscle mass indirectly.
Purpose: Detects abnormal albumin excretion normalized to creatinine.
Indicates: Early kidney damage; preferred for screening diabetic nephropathy.
Purpose: Measures total protein excretion normalized to creatinine.
Indicates: Degree of proteinuria, important for glomerular diseases.
Purpose: Quantifies total protein/albumin excretion.
Indicates: More accurate measurement of proteinuria than spot tests.
Purpose: Imaging to check kidney size, shape, obstruction.
Indicates: Structural abnormalities, obstruction, chronic damage.
Purpose: Measures blood electrolytes.
Indicates: Kidney’s ability to regulate electrolyte balance and acid-base status.
Purpose: Microscopic examination of urine sediment.
Indicates: Presence of red blood cells, white blood cells, casts, crystals suggesting specific diseases.
Purpose: Blood marker of kidney function independent of muscle mass.
Indicates: Alternative to creatinine for estimating GFR.
Kidney biopsy: For diagnosing specific glomerular or interstitial diseases.
Serology: Autoimmune markers (ANA, ANCA, complement) if vasculitis or lupus suspected.
Imaging: CT scan or MRI if structural abnormalities or masses suspected.
Step | Test(s) | Purpose |
---|---|---|
Screening | Serum creatinine, eGFR, urinalysis, ACR | Assess baseline kidney function and damage |
Confirm proteinuria | 24-hour urine protein/albumin, PCR | Quantify protein loss |
Assess structure | Renal ultrasound | Check for obstruction or anatomical issues |
Evaluate cause | Urine microscopy, serology, biopsy if needed | Identify underlying kidney disease cause |