Back Lichenoid drug eruption due to metoprolol. 21 Feb, 2026

Abhi, this is clinically very suggestive of a lichenoid drug eruption due to metoprolol.

👉 Onset 6 months after starting metoprolol fits perfectly with drug-induced lichen planus (usually weeks to months).


🔎 What This Likely Is

✅ Lichenoid Drug Eruption (LDE)

  • Triggered by medications (beta blockers are known causes)

  • Looks like classical lichen planus

  • Appears months after drug initiation

  • Improves after stopping the offending drug

Metoprolol is a documented cause.


📋 What You Should Do (Clinical Approach)

1️⃣ Confirm Timeline

  • Lesions started after metoprolol?

  • Any other new drug added in last 6–12 months?

    • NSAIDs?

    • ACE inhibitors?

    • Antimalarials?

    • Thiazides?

If metoprolol is the only new drug → strong suspicion.


2️⃣ Don’t Stop Abruptly

⚠ Very important
Metoprolol must be tapered, not stopped suddenly.


3️⃣ Switch Antihypertensive

Since patient also had tachycardia (as you mentioned earlier), best alternatives:

✔ Diltiazem (if no heart failure)

  • Controls BP

  • Controls HR

  • Good substitute

OR

✔ ACE inhibitor (e.g., Ramipril)

If tachycardia is mild and secondary.

Avoid:

  • Amlodipine alone (may worsen tachycardia)

  • Hydralazine


4️⃣ Dermatology Management

  • Topical high-potency steroid (Clobetasol)

  • Antihistamine if itching

  • Oral steroids only if severe

Lesions usually improve within weeks–months after withdrawal.

🎯 My Clinical Suggestion

If:

  • Clear timeline

  • No other new drugs

  • No other trigger

👉 I would gradually taper metoprolol and shift to Diltiazem, unless contraindicated.