💊 Frisium (Clobazam)

• Frisium is the brand name for Clobazam, a benzodiazepine.

• It is NOT a fever medicine.

• Its main use in pediatrics:

  • Epilepsy (as an add-on anti-seizure drug).

  • Febrile seizures (seizures triggered by high-grade fever in infants/toddlers).

✅ Why Used in High-Grade Fever

• In some infants/toddlers, high fever (>101–102°F / 38.5–39°C) can trigger febrile seizures.

• Doctors may prescribe Frisium (Clobazam) 2.5 mg for a short course (1–3 days during fever) to prevent recurrence of febrile seizures.

• It works by calming the overactive brain activity during fever.

⚠️ Important Points

• Not an antipyretic → Frisium does not reduce fever (that’s the role of paracetamol/ibuprofen).

• It is only for seizure prevention during fever in children with a history of febrile seizures.

• Should not be given routinely in every child with fever.

• Side effects: sleepiness, drowsiness, reduced alertness, rarely breathing suppression (so dose must be very precise).

✅ Usual Pediatric Dose (as used in febrile seizures, per IAP/AIIMS protocol)

• 0.5–1 mg/kg/day, given in 2 divided doses, for 2–3 days during the febrile illness.

• Example: A 12 kg toddler → ~6–12 mg/day → doctors may prescribe Frisium 2.5 mg once or twice daily depending on risk.

• Always doctor-supervised — not to be given without medical advice.

👉 In Summary

• Frisium 2.5 in high fever is not for treating fever, but to prevent febrile seizures in infants/toddlers who have a history of such seizures.

• It is a temporary protective medicine, not a regular fever drug.

• Always given along with paracetamol/ibuprofen (for fever control).