Back Drug–Disease (Adverse Effect) Pairs 21 Feb, 2026
Health Health
  • Report Note

🫀 Cardiovascular

  1. ACE inhibitors → Dry cough / Angioedema

  2. ARBs → Hyperkalemia

  3. Thiazides → Hyperuricemia (Gout)

  4. Thiazides → Hypercalcemia

  5. Loop diuretics → Hypokalemia

  6. Spironolactone → Gynecomastia

  7. Hydralazine → Drug-induced lupus

  8. Procainamide → Drug-induced lupus

  9. Amiodarone → Pulmonary fibrosis

  10. Amiodarone → Hypo/Hyperthyroidism

  11. Beta blockers → Bradycardia

  12. Beta blockers → Lichenoid eruption

  13. Heparin → HIT (Thrombocytopenia)

  14. Warfarin → Skin necrosis

  15. Statins → Myopathy / Rhabdomyolysis

🧠 CNS

  1. Antipsychotics → Parkinsonism (EPS)

  2. Antipsychotics → Tardive dyskinesia

  3. Haloperidol → Neuroleptic malignant syndrome

  4. SSRIs → SIADH (Hyponatremia)

  5. Benzodiazepines → Dependence

  6. Valproate → Hepatotoxicity

  7. Carbamazepine → Agranulocytosis

  8. Lithium → Hypothyroidism

  9. Lithium → Nephrogenic diabetes insipidus

  10. Isoniazid → Peripheral neuropathy

🧴 Dermatology

  1. Sulfonamides → Stevens–Johnson syndrome

  2. Carbamazepine → SJS/TEN

  3. Allopurinol → SJS/TEN

  4. Phenytoin → Gingival hyperplasia

  5. Nifedipine → Gingival hyperplasia

  6. Steroids → Acne / Cushingoid features

  7. Steroids → Osteoporosis

  8. Chloroquine → Hyperpigmentation

  9. Minocycline → Skin pigmentation

🫁 Respiratory

  1. Bleomycin → Pulmonary fibrosis

  2. Nitrofurantoin → Interstitial lung disease

  3. ACE inhibitors → Dry cough

🩸 Hematology

  1. Clozapine → Agranulocytosis

  2. Linezolid → Thrombocytopenia

  3. Methotrexate → Pancytopenia

  4. Chloramphenicol → Aplastic anemia

🧪 Endocrine / Metabolic

  1. Steroids → Hyperglycemia / Diabetes

  2. Thiazides → Hyperglycemia

  3. Metformin → Lactic acidosis

  4. Propylthiouracil → Agranulocytosis

  5. Amiodarone → Thyroid dysfunction

🦴 Bone & Muscle

  1. Fluoroquinolones → Tendon rupture

  2. Statins → Myopathy

👶 Special High-Yield Pairs

  1. Tetracycline → Teeth discoloration (children)

  2. Chloramphenicol → Gray baby syndrome

🎯 Ultra-High Yield Mnemonics

For exams, remember:

  • Hydralazine, Procainamide, INH → Lupus

  • SJS = Sulfa, Carbamazepine, Phenytoin, Allopurinol

  • Gingival hyperplasia = Phenytoin, Nifedipine, Cyclosporine

  • Pulmonary fibrosis = Amiodarone, Bleomycin, Methotrexate

  • Hyperkalemia = ACEI, ARB, Spironolactone